4 Sisters Wine Bar & Tapas Restaurant Menu (2025 Update)

Welcome to 4 Sisters Wine Bar & Tapas Restaurant, where culinary creativity meets a vibrant atmosphere in the heart of La Crosse, WI. This inviting venue offers an eclectic menu that seamlessly blends tapasy options with hearty entrees, making it perfect for both casual gatherings and special occasions.

  • Tapas: Indulge in generous portions like the Empanadas, filled with savory ground beef and gruyere, or the delightful 4 Sisters Stromboli, a flaky pastry brimming with Italian meats and cheeses.
  • Entrees: Savor dishes such as the Teriyaki Salmon Bowl, featuring a perfectly caramelized salmon filet, or the Tenderloin Salad, packed with flavor and fresh ingredients.

The menu is designed for sharing, making it an excellent choice for friends and families. With flavors that resonate and a lively ambiance, 4 Sisters Wine Bar & Tapas Restaurant truly elevates your dining experience.

TAPAS

HOT SPINACH AND ARTICHOKE DIP

Chopped spinach and artichoke hearts come together to make our famous creamy dip. Served with pita and homemade tortilla chips (gluten free with tortilla chips only)

US$10.99

OAXACA BRAISED CHICKEN QUESADILLA

Chicken braised with lime juice, ancho, guajillo and chipotle pepper, filled in a crispy flour tortilla with roasted corn, poblano peppers, Cotija and Oaxaca cheeses, topped with mixed greens, radishes, and special sauce

US$13.99

FATBOY (QTY 6) GF

Succulent shrimp stuffed with our signature horseradish cream cheese, served with cocktail sauce

US$13.99

BACON WRAPPED SHRIMP (QTY 6) GF

Marinated shrimp wrapped in bacon seared to perfection, served with lemon Sriracha aioli

US$11.99

CHEESE JOURNEY (V) GF

A variety of local and imported cheeses served with seasoned pretzels, stuffed peppadews, dipping oil, Caprese skewer, olives, seasonal fruit, nuts, pita chips, warm bread and a signature compound butter (GF with substitution)

US$24.99

GRILLED CHEESE DIPPERS (V)

Sourdough bread spread with a Dijon butter and topped with a mixture of white wine, white cheddar, gruyere and Boursin cheese, served with vodka marinara dipping sauce

US$11.99

4 SISTERS STROMBOLI

Puff pastries filled with our favorite Italian meats; ham, pepperoni and pastrami, sprinkled with mozzarella and smoked gouda cheeses, baked until it’s flaky and crispy. Served with vodka marinara on the side

US$10.99

EMPANADA (QTY 6)

Flaky puffed pastry filled with lean ground beef, gruyere cheese, onions and bell peppers, drizzled with house-made buttermilk herb sauce

US$13.99

MINI BLEU BURGERS (QTY 4)

Certified Angus Beef patties, sauteed sweet onions, bleu cheese, bacon and horseradish-herb cream cheese, served on mini pretzel buns served with seasoned kettle chips. 12 order 8.49 (GF when bread is substituted 2.50)

US$15.99

GARLIC TERIYAKI EDAMAME (V)

Sauteed Edamame bean pods tossed in a sweet and spicy teriyaki sauce

US$6.99

CARNITAS PLATTER (QTY 4) GF

Mounds of juicy pork carnitas accompanied by homemade salsa, lime cilantro onions, salsa verde, cotija cheese and sour cream. Served with house-made tortilla chips and mini flour or corn tortillas (GF with corn tortillas)

US$14.99

FISH TACOS (QTY 4)

GF with corn tortillas Wild Atlantic cod filets with southwest seasoning, served with chipotle cilantro slaw, house-made salsa, drizzled with a tangy cilantro-lime sauce, topped with crumbled cotija and served on mini flour tortillas (GF with corn tortillas) 12 order 7.99

US$14.99

AHI TUNA BITES

GF with cucumber bites Perfectly seared Ahi tuna rest on top a crisp pita chip, topped with a Kimchi-style slaw, drizzled with wasabi aioli and lightly sprinkled with green onions and sesame seeds. Served with pita chips.

US$12.99

PEPPER JELLY CREAM CHEESE

GF when you substitute gluten free crackers for pita chips Generous mound of cream cheese, topped with our signature pepper jelly, served with house-made pita chips

US$9.99

STUFFED PEPPADEWS (QTY 8) (V) GF

Succulent sweet peppers stuffed with goat cheese

US$5.99

MARGHERITA PIZZA (V)

Crisp flatbread with fresh roma tomatoes, Wisconsin mozzarella & locally grown hydroponic basil, drizzled with a balsamic glaze

US$13.99

WHITE CHEDDAR CHICKEN PIZZA

Crisp flatbread topped with a white sauce, juicy chicken breast, fresh spinach greens, roasted garlic, tomato, red onion, parmesan and white cheddar

US$16.99

SWEET AND SPICY BACON WRAPPED CHICKEN (QTY 8) GF

Generous sized chicken pieces marinated in a brown sugar chili glaze, wrapped in bacon and baked until crisp & tender, drizzled with sweet chili... This dish is a real crowd pleaser

US$11.99

CHICKEN SALAD (QTY 8) GF

Signature chicken salad made up of roasted chicken breast, pecans, grapes in Chef’s signature mayo, served with warm ciabatta bread. GF sub cucumbers for bread

US$9.99

BANG BANG SHRIMP TACOS (QTY 4)

GF with corn tortillas Bite sized shrimp tossed in our house-made sweet and tangy bang bang sauce, chili lime slaw, sprinkled with micro cilantro. Served on mini flour tortillas.

US$13.99

GOAT CHEESE MARINARA

Warm goat cheese covered in house-made marinara, served with warm ciabatta bread

US$12.99

GOURMET MAC & CHEESE

Not your typical Mac & Cheese. Noodles are smothered in a delicate sauce of goat cheese, cream cheese, and parmesan cheese. Baked to perfection and then drizzled with a touch of honey

US$10.99

THAI CHICKEN PIZZA

Spicy Thai chicken breast, tangy peanut sauce, crunchy roasted peanuts, crisp carrots, cilantro and mozzarella cheese drizzled with sweet chili sauce on Artisan crust

US$16.99

Sausage & Pepperoni Pizza

Crisp crust covered with our house-made marinara sauce, topped with Italian sausage, pepperoni & a blend of cheeses

US$16.99

Patatas Bravas

Sliced red potatoes baked in olive oil and topped with grated parmesan, parsley & sriracha bourbon sauce

US$8.99

TENDERLOIN MEDALLION

A pair of 4oz juicy tenderloins, grilled, pan seared and seasoned to perfection. Choose to top your medallions with a creamy gorgonzola sauce or whiskey butter sauteed mushrooms and onions. Served with delicately seasoned fingerling potatoes, seasonal vegetables and garlic bread. Add creamy gorgonzola sauce (2.49) Add whiskey butter-sauteed mushrooms & onions (3.49)

US$29.99

RIBEYE STEAK

8oz. Ribeye steak pan seared & delicately seasoned with seasonal vegetables & red potato loaded mashers

US$28.99

RUSTIC RIBEYE STEAK

8oz Ribeye steak seasoned in a robust blend of garlic and herbs, pan seared, served with butternut squash & patatas bravas

US$29.99

CHICKEN POT PIE

Our signature chicken pot pie, consists of chicken breast, baby carrots, snow peas & roasted corn topped with grandma’s flakey puffed pastry crust with garlic bread

US$17.99

CHICKEN ALFREDO

Our chicken Alfredo with a house-made creamy parmesan sauce served over fettuccine noodles, garlic bread with your choice of blackened or regular chicken breast

US$18.99

WHITE CHICKEN CHILI

Our white chili chicken soup transformed. Basmati rice mixed with northern beans & corn, topped with a 7oz chicken breast smothered in a creamy white chili sauce, accompanied by chips, cotija cheese & sour cream on the side

US$20.99

SURF & TURF

4oz juicy tenderloin grilled, pan seared & seasoned to perfection and large sauteed shrimp served with fingerling potatoes, seasonal vegetables & garlic bread

US$26.99

WHITE CHEDDAR SALMON

A crusted parmesan & white cheddar cheese 8oz salmon filet atop a house-made mixture of a hearty white sauce, fresh spinach greens, roasted garlic, tomato, red onion & garlic bread

US$27.99

ACORN STUFFED SQUASH

Acorn squash loaded with cheese tortellini tossed in a creamy parmesan sauce with a hint of nutmeg then baked to perfection with garlic bread

US$18.99

ITALIAN LASAGNA

Layers piled high with Italian sausage, ricotta, mozzarella, Monterey jack cheddar, smothered in a house-made marinara sauce with garlic bread

US$19.99

TERIYAKI SALMON BOWL

Vegan without salmon. 8oz salmon filet caramelized in house made teriyaki sauce and served segmented in a bowl with basmati rice, freshly steamed carrots, green onion, broccoli & shelled edamame, and delicately sprinkled with sesame seeds

US$26.99

FISH & CHIPS

Walleye filet sauteed in a lemon butter sauce with our house made potato chips & sauce

US$21.99

CREAMY CHARDONAY PASTA

Linguini topped with red onions, tri-color peppers & fresh pea pods, finished with a chardonnay cream sauce Add Shrimp 8 Add Chicken 5

US$15.99

PORTABELLA & SPINACH LASAGNA (V)

Layers piled high with portabella, spinach, ricotta, mozzarella & Parmesan, smothered in a creamy white sauce

US$17.99

QUINOA BOWL (V) GF

Quinoa mixed with edamame, cilantro, red peppers & corn tossed in a lemon vinaigrette and topped with sweet potatoes. Add chicken (4) Add shrimp (7)

US$10.99

CHICKEN CAESAR SALAD

Chopped romaine lettuce topped with 7oz chicken breast, Parmesan cheese, sunflower seeds, chopped bacon, house made croutons & Chefs own Caesar dressing

US$12.99

TENDERLOIN SALAD

Mixed greens, tomato, banana peppers, red onion, bleu cheese crumbles and juicy tenderloin pieces, candied pecans your choice raspberry pomegranate or white balsamic

US$13.99

ENTREES