Welcome to 4 Sisters Wine Bar & Tapas Restaurant
4 Sisters Wine Bar & Tapas Restaurant, located at 100 Harborview Plaza in La Crosse, WI, offers a vibrant dining experience that merges exceptional cuisine with an inviting atmosphere. This restaurant specializes in delectable tapas and enticing entrees, such as rich goat cheese marinara and flavorful creamy Chardonnay pasta. Diners rave about the generous portions of their tapas, with standout dishes like the empanadas and sweet & spicy bacon-wrapped chicken. With an extensive drink menu, including bottomless mimosas on weekends, 4 Sisters is perfect for gatherings. The combination of quick service, exciting flavors, and vibrant outdoor seating makes every visit unforgettable.
- 100 Harborview Plaza #100, La Crosse, WI 54601, United States100 Harborview Plaza #100, La Crosse, WI 54601, United States Hotline: +1 608-782-8213
Welcome to 4 Sisters Wine Bar & Tapas Restaurant, a culinary gem nestled in the heart of La Crosse, Wisconsin. Located at
100 Harborview Plaza #100, this vibrant establishment offers an inviting ambiance perfect for both casual gatherings and special occasions. Whether you're in the mood for a laid-back afternoon with friends or a cozy date night, 4 Sisters promises a delightful experience filled with exquisite flavors and generous portions.As the name suggests, the essence of 4 Sisters is reflected not just in its name but also in its warm, family-inspired environment. Here, the menu is a tantalizing journey through a variety of tapas and hearty entrees. Guests rave about the Oaxaca Braised Chicken Quesadilla, a dish laden with the rich flavors of lime, guajillo, and chipotle, all harmoniously enveloped in a crispy tortilla. Another stellar option is the warm Goat Cheese Marinara, a comforting delight served with fresh ciabatta bread, ideal for sharing or a satisfying light meal.
As I explored the menu, I couldn’t help but be drawn to the dishes that patrons are frequently raving about. The Empanadas, hailed by many as a must-try, showcase the kitchen’s ability to blend tradition with inventiveness, highlighted by their incredible flavor profiles. For those with heartier appetites, the 8oz Ribeye Steak and Tenderloin Salad promise to impress, with each plate demonstrating an elegant presentation and a balance of taste that speaks to meticulous preparation.
The atmosphere here is buzzing—perfect for vibrant group dinners or intimate meals. You might find yourself indulging in their acclaimed bottomless mimosas available on Saturdays, a fantastic find for a leisurely brunch. Not to mention, the mojito and mule flight drinks provide a refreshing twist to complement your meal, enhancing the overall dining experience.
As I take in the surroundings, I can’t help but admire the creativity and effort that has gone into curating such a diverse menu at 4 Sisters. Whether you’re celebrating a momentous occasion or simply enjoying a night out, the focus on quality and customer satisfaction is evident in every dish. The rave reviews from guests like Jeremy Gray and Jaita Ghosh validate this sentiment, praising the flavors and generous portions that typically exceed expectations.
In summary, 4 Sisters Wine Bar & Tapas Restaurant is not merely a destination for food; it’s an experience. From the robust flavors of their tapas to the inventive approach to entrees, the culinary offerings are tailored to thrill your taste buds. Pair that with an inviting atmosphere and exceptional service, and you have a must-visit spot on your dining list.

Stopped by here this afternoon with a buddy and my father and had a lovely time. Be careful ordering too many tapas as they aren't normal size tapas, but more of meal size tapas. We started out ordering the; Mini Blu Burgers, Fish Tacos and Empenadas to kick off the meal and each one was full of flavor, but if i had to pick, the empenadas stole the show. For our main dishes we ordered; The blackend shrimp alfredo, Buffalo Trace beef tips and the tenderloin salad. Each plate was delicious in their own way and definitely will be back!

Yum on all accounts! The only downside is it is pretty pricey. However, the bottomless mimosas on Saturdays 11-2 are hard to beat at only 12. One side of the menu is shareable tapas and the other side is full meals. I absolutely loved the avocado blackened shrimp bites. Everyone loved what they ordered. The service is quick, and it's a good place for a larger group because they take reservations. Highly recommend!

Fantastic food! They have something for everyone. Highly suggest the mojito and mule flights! Even have amazing outdoor seating

We choose this place for my birthday lunch & the food was par excellence. They have an exciting menu. We definitely recommend their sweet & spicy bacon wrapped chicken, It's a treat to your taste buds. Gouda bacon chicken was so creamy & cheesey, just the way I like it. Their Street Corn chicken was something really unique we tried, cilantro added with the rice gave it a exciting twist of flavors. Their food portion is sufficient and the quality is top notch.

Highly recommend this place with some friends and time. We ordered entrees which were amazing. But I'd love to go back and order an assortment of tapas and just enjoy and drink. Atmosphere was upbeat

We ordered •Call Me Honey drink •avocado blackened shrimps •sweet and spicy bacon wrapped chicken (definitely my favorite and the most filling) •creamy bacon gouda dip •fish tacos It is one of the best shareable restaurants I have tried. Everything we ordered was 5 star quality. I was so full but it was delicious and I wanted to keep eating!

Quite honestly, I could go on and on about 4 Sisters Wine Bar & Tapas. I was so impressed with this restaurant. My mom said that last time they were in lacrosse that day had a meal here and really liked it. Boy was that an understatement. They have a beautiful patio space overlooking the riverfront park and the river itself. Inside the restaurant is cozy, but not crammed, all of the staff was very friendly, and I was absolutely floored by the quantity and quality of food you get for the prices on the menu. To give you an idea of the prices, we ordered these two “starters“ and after a 20% tip, it was still under 40. We had such a hard time deciding what to get. My mom remembered having the nachos and raved about them so we had to go with that and we opted for adding shrimp. Then, almost anytime I see ahi tuna on the menu I have to get it. The tuna was light and refreshing, but the star of the show were these nachos with fresh chips, layered toppings, so that it wasn’t all just on top, the bang bang sauce on them was spicy, but not overpowering, and there was plenty of shrimp throughout. They are happy hour specials had good drink prices and their bourbon list was possibly the most impressive one I have seen in a restaurant date. If you’re staying in the cross, passing through, or just need an excuse to explore a beautiful city, I’m sold. After eating there we drove down through the riverfront park and the city’s tribute to their sister cities was BEAUTIFUL. I’m definitely going to make time to go through there again.

Outstanding!!! Choices, flavors, service brought us back 3 nights in a row while in town. Love this place. Sitting outside or at the bar just a top notch resturant. The Jalapeno martini was second to none. The seared tuna plate very fresh, the chicken bites very very good .... I would highly recommend eating or getting a drink here !!!